ACP Medicine
نویسندگان
چکیده
Sepsis, along with the multiorgan failure that often accompanies the systemic inflammatory response syndrome (SIRS), is a leading cause of mortality in the intensive care unit. As many as 700,000 patients develop sepsis annually in the United States. Nearly half of these patients manifest severe sepsis and septic shock. The mortality for septic shock remains approximately 35% to 45%, despite a concerted effort to improve the treatment options and outcome. Septic shock has become a major focus of critical care research. Although modest improvements in the prognosis have been made over the past 2 decades and promising new therapies have appeared in the past few years, innovations in the management of septic shock are still required. This chapter reviews some of the remarkable advances achieved in the understanding of the molecular pathophysiology of sepsis, the diagnostic and therapeutic strategies emerging from this research, and the current management of septic shock.
منابع مشابه
Advances in evidence-based information resources for clinical practice.
Readers with a critical eye for value will quickly discern that ACP Journal Club just got bigger and better. The usual 25 pages of abstracts in each issue have been expanded to 37 by adding 12 pages of unique content from ACP Journal Club’s sister journal, Evidence-Based Medicine. This additional content covers advances of relevance to primary care specialists in the fields of family medicine, ...
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Background: Neisseria meningitidis, a life-threatening human pathogen with the potential to cause large epidemics, can be isolated from the nasopharynx of 5–15% of adults. The aim of the current study was to evaluate biophysical and biochemical properties and immunological aspects of chimeric acyl-carrier protein-macrophage infectivity potentiator protein-type IV pilus biogenesis protein ...
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OBJECTIVE The effect of acupuncture (ACP) on regional cerebral blood flow (rCBF) is unclear. Single-photon emission computed tomography studies on three patients with dystonia were performed before and after ACP treatment to test the contention that ACP affects rCBF. METHODS Pre-ACP and post-ACP CBF study were performed on the same day; 99mTc ethyl cysteinate dimer was injected for each study...
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Complementary and alternative medicine (CAM) is no longer new terminology in the healthcare system but, evidence-based CAM is still an unfamiliar term. Evidence-based medicine, a practice of medicine based on the recommendation derived from a systematic, scientific study of published data, is accepted as the standard in the healthcare. ACP Evidence-Based Guide to Complementary and Alternative M...
متن کاملReviewing the reviewers: the quality of reporting in three secondary journals.
BACKGROUND Secondary journals such as ACP Journal Club (ACP), Journal Watch (JW) and Internal Medicine Alert (IMA) have enormous potential to help clinicians remain up to date with medical knowledge. However, for clinicians to evaluate the validity and applicability of new findings, they need information on the study design, methodology and results. METHODS Beginning with the first issue in M...
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